Cannabinoids Connections: Mental Disease And Everything In Between

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There are many studies on the relationship between cannabinoids use and mental illnesses. It is potentially a medicine box, it has so many various cannabinoids and it offers new ways to treat mental illness. This explains why a lot of people with mental diseases tend to buy cheap weed for sale in the legal market and use medical cannabis as treatment.

What Are Cannabinoids?

Naturally, cannabinoids are chemical compounds that can interact, in any or another way, with cannabinoid receptors. Such compounds can be classified into cannabimimetics—they exhibit cannabinoid action and are mostly CB1 receptor agonists, and antagonists competent of coupling to cannabinoid receptors— they provide no cannabinoid effects, simply blocking these receptors for other substances. The term “cannabinoids” covers compounds having diverse chemical structures underlying the conventional classification.

There are more than 80 cannabinoids. The Tetrahydrocannabinol (THC), the best examined and possibly the most psychoactive ingredient in cannabis and cannabidiol (CBD) have opposing results, and different genetic or strains have different levels of cannabinoids.

Cannabinoids exist largely in the plant as their carboxylic precursors Tetrahydrocannabinolic acid and Cannabidiolic acid and are decarboxylated by light or heat while in storage or when combusted.

THC is synthesized inside the secretory trichomes present in the flowers, leaves, and branches of the female plant. It yields a common precursor, olivetolic acid, with another quantitatively important component is CBD in which is the amplest cannabinoid in hemp. For this reason, the genetic profile and relative level of representation of the enzymes responsible for their synthetic genotype, namely THCA synthase and CBDA synthase, define the chemical composition of a particular cultivar (chemotype).


Cannabis is very helpful for anxiety, which is often experienced by patients dealing with cancer, chronic pain, and other conditions for which cannabis is helpful. Medical cannabis may slow down thought processes, helping break up some of the upsetting thought patterns that anxiety sufferers have to deal with.

Cannabis users in general, report fewer episodes of depression than non-smokers. Usage in depression can help break up negative thought cycles that may lead to a debilitating episode. Marijuana does not magically treat depression and will not cure the root problem leading to it. However, it can help considerably with mood while the patient works with a professional to treat the root cause.

Medical cannabis may calm mood swings substantially that are seen with bipolar disorder. Medical cannabis helps with these numerous mental conditions substantially. It provides an excellent alternative to traditional medications which often have considerable side effects and may have substantial costs as well.

Alzheimer’s disease

Recent medical research suggests that the use of medical cannabis could play a significant role in reducing the progression of the dreaded Alzheimer’s disease. Tetrahydrocannabinol or THC that is its primary ingredient reduces and prevents the formation of neural protein deposits deep within the brain. These deposits are primarily responsible for this degenerative neural condition.

Medical cannabis that is supplied by medical cannabis dispensaries control the formation of these protein deposits or sticky amyloid plaques that result in neuronal damage, inhibits memory and cognition, cause severe loss of memory, and lead to confusion, irritability, mood swings, spatial disorientation, and speech problems.

The progressive and fatal Alzheimer’s disease destroys brain cells, which results in loss of memory, dementia, and disturbed motor skills along with diminished intellect and social skills. Alzheimer’s disease is among the top ten causes of death in the elderly in the United States. Research indicates that medical cannabis represents an effective drug treatment for Alzheimer’s disease and some of its symptoms.

Posttraumatic stress disorder (PTSD

Posttraumatic stress disorder (PTSD) trips inside a broader trauma- and stressor-related ailments categorized by the Diagnostic and Statistical Manual of Mental Disorders. The diagnostic criteria of PTSD involve an exposure to a traumatic event like the threat of death, serious injury, or sexual violence and presenting a psychological distress symptoms that occur as a result of that vulnerability like the intrusion symptoms, such as distressing memories; delay of stimuli that are associated with the traumatic event; adverse alterations in mood and cognition; changes in arousal and reactivity associated with the traumatic event; functional impairment.

Sleep disorders

Sleep disorders can be categorized into principal groups that include insomnia, sleep-related breathing disorders, parasomnias, sleep-related movement disorders, and circadian rhythm sleep-wake disorders. There is some data to recommend that the endocannabinoid system may have a role in sleep.

THC is correlated in a dose-dependent manner with changes in slow-wave sleep, which is crucial for learning and memory consolidation. Cannabinoids may also have effects on sleep latency, reducing time to sleep onset at low doses and improving time to sleep onset at higher doses. Thus, cannabinoids could have a role in treating sleep disorders. Some people with insomnia also grow medical marijuana autoflower seeds and extract its natural compound at the comfort of their homes.


Depression is one of the nation’s most well-known mental health disorders. Across the many depressive disorders that exist like persistent depressive disorder, major depressive disorder and, premenstrual dysphoric disorder there are common symptomatic traits of feelings of sadness, emptiness, or irritable mood, accompanied by bodily and cognitive changes that affect the individual’s capacity to function. The endocannabinoid system is known to play a role in mood regulation.

Bottom Line

Given the known psychoactive effects of some cannabinoids, trials and studies on the effects of different types of cannabis with varying THC and CBD content on mental disorder symptoms gives a promising medical potential. The result adds substantially to the information center, expanding the range of cannabinoids evaluated and the possibility to examine the consistency of effects beyond studies.


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